The field of computer-aided vaccine design faces many challenges. Perhaps the greatest is to identify protective antigens; proteins which can serve as potential vaccine candidates.In the past, attempts have been made to collect and compile known antigenic regions, or epitopes, which may stimulate B and T cell responses (MHCBN, BCIPEP, AntiJen, IEDB). However, such epitope databases while providing comprehensive information about experimentally validated epitopes within proteins they do not cover a wide range of known antigens. We have developed a database 'AntigenDB' which provides comprehensive information about a wide range of experimentally-validated antigens. The structure of AntigenDB is outlined below:

If you are using AntigenDB database, Please cite:
Ansari HR, Flower DR, Raghava GP. AntigenDB: an immunoinformatics database of pathogen antigens.
Nucleic Acids Res. 2009 Oct 9.[PMID: 19820110] [Epub ahead of print]
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