1DYQ Enterotoxin date Feb 05, 2000
title Staphylococcal Enterotoxin A Mutant Vaccine
authors H.I.Krupka, B.W.Segelke, B.Rupp
compound source
Molecule: Staphylococcal Enterotoxin A Mutant
Chain: A
Synonym: Sea
Engineered: Yes
Mutation: Yes
Organism_scientific: Staphylococcus Aureus
Strain: A
Expression_system: Escherichia Coli
Expression_system_strain: Jm101
Expression_system_plasmid: Pse380
Expression_system_gene: Fda196e
Other_details: Mutant Gene
symmetry Space Group: P 21 21 21
R_factor 0.191
crystal
cell
length a length b length c angle alpha angle beta angle gamma
39.048 78.652 86.374 90.00 90.00 90.00
method X-Ray Diffractionresolution 1.50 Å
ligand SO4, ZN enzyme
note 1DYQ is a representative structure
related structures by homologous chain: 1ESF
similarity Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_tox_C]
subunit Monomer.
subcellular loc. Secreted protein.
Gene ENTA (S. aureus)
function The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome.
Gene
Ontology
ChainFunctionProcessComponent
A
  • zinc ion binding
  • metal ion binding
  • pathogenesis
  • extracellular region
  • Primary referenceStructural basis for abrogated binding between staphylococcal enterotoxin A superantigen vaccine and MHC-IIalpha., Krupka HI, Segelke BW, Ulrich RG, Ringhofer S, Knapp M, Rupp B, Protein Sci 2002 Mar;11(3):642-51. PMID:11847286
    Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (52 Kb) [Save to disk]
  • Biological Unit Coordinates (1dyq.pdb1.gz) 49 Kb
  • CSU: Contacts of Structural Units for 1DYQ
  • Likely Quarternary Molecular Structure file(s) for 1DYQ
  • Structure Factors (388 Kb)
  • Retrieve 1DYQ in mmCIF format [Save to disk]
  • View 1DYQ in 3D
  • Proteopedia, because life has more than 2D.
  • On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure.
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  • Cartoon representation from PDB Cartoon
  • Ramachandran plot from PDBSum
  • Structure-derived information
  • Conformational Epitope Prediction for 1DYQ from the CEP Server.
  • Electron Density related parameters from EDS Electron Density Server, at Upsala
  • Dipole moment, from Dipole Server at Weizmann Institute
  • Crystal Contacts, from CryCo at Weizmann Institute
  • 3D motif for 1DYQ, from MSDmotif at EBI
  • Classification of representative domains in scop (Structural Classification of Proteins)
        - Domain d1dyqa2, region A:121-233 [Jmol] [rasmolscript] [script source]
        - Domain d1dyqa1, region A:6-120 [Jmol] [rasmolscript] [script source]
  • Fold representative 1dyq from FSSP and Dali (Families of Structurally Similar Proteins)
  • Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH
  • Summaries and structural analyses of PDB data files from PDBSum
  • Identification of Protein Pockets & Cavities at CASTp
  • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1dyq_A]
  • Other resources with information on 1DYQ
  • InterPro: IPR006123 , IPR006173 , IPR006177 , IPR006126
  • PDBREPORT (protein verification by WHAT_CHECK procedures)
  • MMDB (Entrez's Structure Database)
  • Movements, Movies and Images
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