1ESF Enterotoxin date May 25, 1995
title Staphylococcal Enterotoxin A
authors E.M.Schad, L.A.Svensson
compound source
Molecule: Staphylococcal Enterotoxin A
Chain: A, B
Engineered: Yes
Organism_scientific: Staphylococcus Aureus
Expression_system: Escherichia Coli
symmetry Space Group: P 1 21 1
R_factor 0.204
crystal
cell
length a length b length c angle alpha angle beta angle gamma
53.600 62.500 75.100 90.00 96.00 90.00
method X-Ray Diffractionresolution 1.90 Å
ligand CD enzyme
related structures by homologous chain: 1DYQ, 1I4G
similarity Belongs to the staphylococcal/streptococcal toxin family.[Stap_Strp_tox_C]
subunit Monomer.
subcellular loc. Secreted protein.
Gene ENTA (S. aureus)
function The illness characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome.
Gene
Ontology
ChainFunctionProcessComponent
A, B
  • zinc ion binding
  • metal ion binding
  • pathogenesis
  • extracellular region
  • Primary referenceCrystal structure of the superantigen staphylococcal enterotoxin type A., Schad EM, Zaitseva I, Zaitsev VN, Dohlsten M, Kalland T, Schlievert PM, Ohlendorf DH, Svensson LA, EMBO J 1995 Jul 17;14(14):3292-301. PMID:7628431
    Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (82 Kb) [Save to disk]
  • Biological Unit Coordinates (1esf.pdb1.gz) 43 Kb
  • Biological Unit Coordinates (1esf.pdb2.gz) 39 Kb
  • CSU: Contacts of Structural Units for 1ESF
  • Likely Quarternary Molecular Structure file(s) for 1ESF
  • Structure Factors (438 Kb)
  • Retrieve 1ESF in mmCIF format [Save to disk]
  • View 1ESF in 3D
  • Proteopedia, because life has more than 2D.
  • On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure.
  • On FirstGlance, an excellent tool for a guided tour on the structure components, by E. Martz.
  • On AstexViewer, from MSD-EBI (viewer documentation).
  • On RasMol (Install RasMol freeware) Here's help on how to use RasMol.
  • Visual 3D analysis of 1ESF
  • Protein Explorer, Easier to use and more powerful than RasMol. (Win and Mac only)
  • Noncovalent Bond Finder displays the closest contacts to ligand or interface, reports distances, walks over water bridges.
  • Cartoon representation from PDB Cartoon
  • Ramachandran plot from PDBSum
  • Structure-derived information
  • Electron Density related parameters from EDS Electron Density Server, at Upsala
  • Dipole moment, from Dipole Server at Weizmann Institute
  • Crystal Contacts, from CryCo at Weizmann Institute
  • 3D motif for 1ESF, from MSDmotif at EBI
  • Genome occurence of 1ESF's fold from GeneCensus
  • Classification of representative domains in scop (Structural Classification of Proteins)
        - Domain d1esfa1, region A:1-120 [Jmol] [rasmolscript] [script source]
        - Domain d1esfa2, region A:121-233 [Jmol] [rasmolscript] [script source]
        - Domain d1esfb1, region B:1-120 [Jmol] [rasmolscript] [script source]
        - Domain d1esfb2, region B:121-233 [Jmol] [rasmolscript] [script source]
  • Fold representative 1esf from FSSP and Dali (Families of Structurally Similar Proteins)
  • Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH
  • Summaries and structural analyses of PDB data files from PDBSum
  • Identification of Protein Pockets & Cavities at CASTp
  • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1esf_B] [1esf_A]
  • Other resources with information on 1ESF
  • InterPro: IPR006123 , IPR006173 , IPR006177 , IPR006126
  • PDBREPORT (protein verification by WHAT_CHECK procedures)
  • MMDB (Entrez's Structure Database)
  • Movements, Movies and Images
  • Domain movements in 1ESF from the Database of Macromolecular Movements.
  • Images from IMB Jena Image Library of Biological Macromolecules.

  • You may enter another PDB ID code
    Go [Back], to the [PDB Lite page], to the [OCA Search page] or to the [PDB Home page]
    OCA© by Jaime Prilusky, 1996-2007
    Bioinformatics and Biological Computing
    Weizmann Institute of Science