1HUF Hydrolase date Jan 04, 2001
title Crystal Structure Of The N-Terminal Domain Of The Tyrosine Phosphatase Yoph From Yersinia Pestis.
authors A.G.Evdokimov, D.S.Waugh
compound source
Molecule: Tyrosine Phosphatase Yoph
Chain: A
Fragment: N-Terminal Domain
Synonym: Virulence Protein
Ec: 3.1.3.48
Engineered: Yes
Organism_scientific: Yersinia Pestis
Organism_common: Bacteria
Gene: Yoph
Expression_system: Escherichia Coli
Expression_system_common: Bacteria
Expression_system_strain: Bl21(De3)-Ril
Expression_system_vector_type: Pdonr201
Expression_system_plasmid: Pkm904
symmetry Space Group: C 2 2 21
R_factor 0.189
crystal
cell
length a length b length c angle alpha angle beta angle gamma
48.063 120.651 49.036 90.00 90.00 90.00
method X-Ray Diffractionresolution 2.00 Å
ligand
enzyme Hydrolase E.C.3.1.3.48 BRENDA
note 1HUF is a representative structure
related structures by homologous chain: 1K46
Gene YOPH (Y. pestis)
Gene
Ontology
ChainFunctionProcessComponent
A
  • protein tyrosine phosphatase...
  • hydrolase activity
  • phosphoric monoester hydrola...
  • protein amino acid dephospho...
  • pathogenesis
  • dephosphorylation

  • Primary referenceStructure of the N-terminal domain of Yersinia pestis YopH at 2.0 A resolution., Evdokimov AG, Tropea JE, Routzahn KM, Copeland TD, Waugh DS, Acta Crystallogr D Biol Crystallogr 2001 Jun;57(Pt 6):793-9. PMID:11375498
    Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (25 Kb) [Save to disk]
  • Biological Unit Coordinates (1huf.pdb1.gz) 21 Kb
  • CSU: Contacts of Structural Units for 1HUF
  • Likely Quarternary Molecular Structure file(s) for 1HUF
  • Structure Factors (163 Kb)
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  • Classification of representative domains in scop (Structural Classification of Proteins)
        - Domain d1hufa_, region A [Jmol] [rasmolscript] [script source]
  • Fold representative 1huf from FSSP and Dali (Families of Structurally Similar Proteins)
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