1IOK	Chaperone	date	Mar 16, 2001
title	Crystal Structure Of Chaperonin-60 From Paracoccus Denitrificans
authors	T.A.Fukami, M.Yohda, H.Taguchi, M.Yoshida, K.Miki
compound		source
Molecule: Chaperonin 60 Chain: A, B, C, D, E, F, G		Organism_scientific: Paracoccus Denitrificans Organism_common: Bacteria
symmetry	Space Group: P 42 21 2	R_factor	0.204
crystal cell	length a length b length c angle alpha angle beta angle gamma 286.355 286.355 153.463 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	3.20 Å
similarity	Belongs to the chaperonin (hsp60) family.[Cpn60_TCP1]
subunit	Oligomer of 14 subunits composed of two stacked rings of 7 subunits (by similarity).
subcellular loc.	Cytoplasm (by similarity).
genes	groL, mopA (P. denitrificans)
function	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (by similarity).
Gene Ontology	Chain Function Process Component F, A, D, C, G, E, B nucleotide binding protein binding ATP binding unfolded protein binding protein folding protein refolding cellular protein metabolic p...
Primary reference	Crystal structure of chaperonin-60 from Paracoccus denitrificans., Fukami TA, Yohda M, Taguchi H, Yoshida M, Miki K, J Mol Biol 2001 Sep 21;312(3):501-9. PMID:11563912

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (554 Kb) [Save to disk] Biological Unit Coordinates (1iok.pdb1.gz) 494 Kb CSU: Contacts of Structural Units for 1IOK Likely Quarternary Molecular Structure file(s) for 1IOK Retrieve 1IOK in mmCIF format [Save to disk]

View 1IOK in 3D

On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure. On FirstGlance, an excellent tool for a guided tour on the structure components, by E. Martz. On AstexViewer, from MSD-EBI (viewer documentation). On RasMol (Install RasMol freeware) Here's help on how to use RasMol.

Visual 3D analysis of 1IOK

Protein Explorer, Easier to use and more powerful than RasMol. (Win and Mac only) Noncovalent Bond Finder displays the closest contacts to ligand or interface, reports distances, walks over water bridges. STING, shows the sequence and maps the locations of sequence residues or residue ranges onto the 3D structure. GRASS (Graphical Representation and Analysis of Structure Server) Cartoon representation from PDB Cartoon Ramachandran plot from PDBSum

Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1IOK, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1ioka3, region A:137-190,A:367-409 [Jmol] [rasmolscript] [script source]     - Domain d1ioka2, region A:191-366 [Jmol] [rasmolscript] [script source]     - Domain d1ioka1, region A:2-136,A:410-526 [Jmol] [rasmolscript] [script source]     - Domain d1iokb3, region B:137-190,B:367-409 [Jmol] [rasmolscript] [script source]     - Domain d1iokb2, region B:191-366 [Jmol] [rasmolscript] [script source]     - Domain d1iokb1, region B:2-136,B:410-526 [Jmol] [rasmolscript] [script source]     - Domain d1iokc3, region C:137-190,C:367-409 [Jmol] [rasmolscript] [script source]     - Domain d1iokc2, region C:191-366 [Jmol] [rasmolscript] [script source]     - Domain d1iokc1, region C:2-136,C:410-526 [Jmol] [rasmolscript] [script source]     - Domain d1iokd3, region D:137-190,D:367-409 [Jmol] [rasmolscript] [script source]     - Domain d1iokd2, region D:191-366 [Jmol] [rasmolscript] [script source]     - Domain d1iokd1, region D:2-136,D:410-526 [Jmol] [rasmolscript] [script source]     - Domain d1ioke3, region E:137-190,E:367-409 [Jmol] [rasmolscript] [script source]     - Domain d1ioke2, region E:191-366 [Jmol] [rasmolscript] [script source]     - Domain d1ioke1, region E:2-136,E:410-526 [Jmol] [rasmolscript] [script source]     - Domain d1iokf3, region F:137-190,F:367-409 [Jmol] [rasmolscript] [script source]     - Domain d1iokf2, region F:191-366 [Jmol] [rasmolscript] [script source]     - Domain d1iokf1, region F:2-136,F:410-526 [Jmol] [rasmolscript] [script source]     - Domain d1iokg3, region G:137-190,G:367-409 [Jmol] [rasmolscript] [script source]     - Domain d1iokg2, region G:191-366 [Jmol] [rasmolscript] [script source]     - Domain d1iokg1, region G:2-136,G:410-526 [Jmol] [rasmolscript] [script source] Fold representative 1iok from FSSP and Dali (Families of Structurally Similar Proteins)

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1iok_A] [1iok_D] [1iok_C] [1iok_F] [1iok_E] [1iok_B] [1iok_G]

Other resources with information on 1IOK

InterPro: IPR002423 , IPR012723 , IPR001844 PDBREPORT (protein verification by WHAT_CHECK procedures) MMDB (Entrez's Structure Database)

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