1R88	Immune System	date	Oct 23, 2003
title	The Crystal Structure Of Mycobacterium Tuberculosis Mpt51 (Fbpc1)
authors	R.A.Wilson, W.N.Maughan, L.Kremer, G.S.Besra, K.Futterer
compound		source
Molecule: Mpt51mpb51 Antigen Chain: A, B Synonym: Fibronectin-Binding Protein C1 (Fbpc1, Mpt51) Engineered: Yes		Organism_scientific: Mycobacterium Tuberculosis Organism_common: Bacteria Gene: Fbpc1 Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: C41(De3) Expression_system_vector_type: Plasmid Expression_system_plasmid: Pet23b
symmetry	Space Group: P 21 21 21	R_factor	0.189
crystal cell	length a length b length c angle alpha angle beta angle gamma 59.900 108.900 109.800 90.00 90.00 90.00
method	X-Ray Diffraction	resolution	1.71 Å
note	1R88 is a representative structure
similarity	Belongs to the mycobacterial a85 antigen family.[Esterase]
subcellular loc.	Secreted protein.
Gene Ontology	Chain Function Process Component A, B acyltransferase activity transferase activity
Primary reference	The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha/beta hydrolases., Wilson RA, Maughan WN, Kremer L, Besra GS, Futterer K, J Mol Biol 2004 Jan 9;335(2):519-30. PMID:14672660

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (102 Kb) [Save to disk] Biological Unit Coordinates (1r88.pdb1.gz) 48 Kb Biological Unit Coordinates (1r88.pdb2.gz) 40 Kb CSU: Contacts of Structural Units for 1R88 Likely Quarternary Molecular Structure file(s) for 1R88 Retrieve 1R88 in mmCIF format [Save to disk]

View 1R88 in 3D

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Visual 3D analysis of 1R88

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Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1R88, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1r88a_, region A [Jmol] [rasmolscript] [script source]     - Domain d1r88b_, region B [Jmol] [rasmolscript] [script source] Fold representative 1r88 from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1r88_B] [1r88_A]

Other resources with information on 1R88

InterPro: IPR000801 MMDB (Entrez's Structure Database)

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