1RVZ	Viral Protein	date	Dec 15, 2003
title	1934 H1 Hemagglutinin In Complex With Lstc
authors	S.J.Gamblin, L.F.Haire, R.J.Russell, D.J.Stevens, B.Xiao, Y Ha, N.Vasisht, D.A.Steinhauer, R.S.Daniels, A.Elliot, D.C.Wiley, J.J.Skehel
compound		source
Molecule: Hemagglutinin Chain: A, C, E, G, I, K Other_details: Hemagglutinin Ha1 Chain		Organism_scientific: Influenza A Virus (Apuerto Rico834(H1n1)); Organism_taxid: 211044 Strain: A-Puerto Rico-8-34 Other_details: Bromelain Digestion
Molecule: Hemagglutinin Chain: B, D, F, H, J, L Other_details: Hemagglutinin Ha2 Chain		Organism_scientific: Influenza A Virus (Apuerto Rico834(H1n1)); Organism_taxid: 211044 Strain: A-Puerto Rico-8-34 Other_details: Bromelain Digestion
symmetry	Space Group: C 1 2 1	R_factor 0.225 R_Free 0.257
crystal cell	length a length b length c angle alpha angle beta angle gamma 227.583 131.522 175.017 90.00 110.07 90.00
method	X-Ray Diffraction	resolution	2 Å
ligand	GAL, NAG, SIA	enzyme
related structures	by homologous chain: 1RU7, 1RVX
Gene Ontology	Chain Function Process Component F, A, J, K, E, B, H, C, D, I, G, L host cell surface receptor b... viral envelope fusion with h... Golgi membrane endoplasmic reticulum membra... plasma membrane membrane integral to membrane virion viral envelope host cell plasma membrane endocytic vesicle membrane virion membrane
Primary reference	The structure and receptor binding properties of the 1918 influenza hemagglutinin., Gamblin SJ, Haire LF, Russell RJ, Stevens DJ, Xiao B, Ha Y, Vasisht N, Steinhauer DA, Daniels RS, Elliot A, Wiley DC, Skehel JJ, Science 2004 Mar 19;303(5665):1838-42. Epub 2004 Feb 5. PMID:14764886

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (522 Kb) [Save to disk] Biological Unit Coordinates (1rvz.pdb1.gz) 259 Kb Biological Unit Coordinates (1rvz.pdb2.gz) 261 Kb CSU: Contacts of Structural Units for 1RVZ Likely Quarternary Molecular Structure file(s) for 1RVZ Retrieve 1RVZ in mmCIF format [Save to disk]

View 1RVZ in 3D

Proteopedia, because life has more than 2D. On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure. On FirstGlance, an excellent tool for a guided tour on the structure components, by E. Martz. On AstexViewer, from MSD-EBI (viewer documentation). On RasMol (Install RasMol freeware) Here's help on how to use RasMol.

Visual 3D analysis of 1RVZ

Protein Explorer, Easier to use and more powerful than RasMol. (Win and Mac only) Cartoon representation from PDB Cartoon Ramachandran plot from PDBSum

Structure-derived information

Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 1RVZ, from MSDmotif at EBI Classification of representative domains in scop (Structural Classification of Proteins)     - Domain d1rvza_, region A [Jmol] [rasmolscript] [script source]     - Domain d1rvzb_, region B [Jmol] [rasmolscript] [script source]     - Domain d1rvzc_, region C [Jmol] [rasmolscript] [script source]     - Domain d1rvzd_, region D [Jmol] [rasmolscript] [script source]     - Domain d1rvze_, region E [Jmol] [rasmolscript] [script source]     - Domain d1rvzf_, region F [Jmol] [rasmolscript] [script source]     - Domain d1rvzg_, region G [Jmol] [rasmolscript] [script source]     - Domain d1rvzh_, region H [Jmol] [rasmolscript] [script source]     - Domain d1rvzi_, region I [Jmol] [rasmolscript] [script source]     - Domain d1rvzj_, region J [Jmol] [rasmolscript] [script source]     - Domain d1rvzk_, region K [Jmol] [rasmolscript] [script source]     - Domain d1rvzl_, region L [Jmol] [rasmolscript] [script source] Fold representative 1rvz from FSSP and Dali (Families of Structurally Similar Proteins) Class (fold), Architecture (subfold), Topology, Homologous superfamily from CATH Summaries and structural analyses of PDB data files from PDBSum Identification of Protein Pockets & Cavities at CASTp

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [1rvz_C] [1rvz_I] [1rvz_A] [1rvz_E] [1rvz_F] [1rvz_G] [1rvz_L] [1rvz_B] [1rvz_D] [1rvz_H] [1rvz_J] [1rvz_K]

Other resources with information on 1RVZ

MMDB (Entrez's Structure Database)

Movements, Movies and Images

Images from IMB Jena Image Library of Biological Macromolecules.

You may enter another PDB ID code

Go [Back], to the [PDB Lite page], to the [OCA Search page] or to the [PDB Home page]

---

OCA© by Jaime Prilusky, 1996-2007
Bioinformatics and Biological Computing
Weizmann Institute of Science

---