1SSN Hydrolase date Jun 07, 1998
title Staphylokinase, Sakstar Variant, Nmr, 20 Structures
authors O.Ohlenschlager, R.Ramachandran, K.H.Guhrs, B.Schlott, L.R.Brown
compound source
Molecule: Staphylokinase
Chain: A
Synonym: Sak
Engineered: Yes
Mutation: Yes
Organism_scientific: Staphylococcus Aureus
Gene: Taq Promotor
Expression_system: Escherichia Coli
Expression_system_strain: Tg1
Expression_system_plasmid: Pmex602sakb
Expression_system_gene: Taq Promotor
methodNMR, 20 Structures
related structures by homologous chain: 1BUI
similarity Belongs to the Staphylokinase family.
subcellular loc. Secreted protein.
Gene SAK (S. aureus)
function Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1. 1 complex with plasmin, which in turn activates other plasminogen molecules.
Gene
Ontology
ChainFunctionProcessComponent
A
  • plasminogen activator activi...


  • Primary referenceNuclear magnetic resonance solution structure of the plasminogen-activator protein staphylokinase., Ohlenschlager O, Ramachandran R, Guhrs KH, Schlott B, Brown LR, Biochemistry 1998 Jul 28;37(30):10635-42. PMID:9692953
    Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (755 Kb) [Save to disk]
  • Biological Unit Coordinates (1ssn.pdb1.gz) 754 Kb
  • CSU: Contacts of Structural Units for 1SSN
  • Original NMR restraints for 1SSN from PDB
  • Experimental data, such as chemical shifts, at BioMagResBank (BMRB)
  • NMR Restraints Grid from BioMagResBank (BMRB)
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  • 3D motif for 1SSN, from MSDmotif at EBI
  • Classification of representative domains in scop (Structural Classification of Proteins)
        - Domain d1ssn__, region [Jmol] [rasmolscript] [script source]
  • Fold representative 1ssn from FSSP and Dali (Families of Structurally Similar Proteins)
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  • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1ssn_A]
  • Other resources with information on 1SSN
  • InterPro: IPR004093
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