1ZZF Transcription date Jun 14, 2005
title The Dna-Bound Solution Structure Of Hpv-16 E2 Dna-Binding Domain
authors T.Eliseo, A.D.Nadra, G.De Prat-Gay, M.Paci, O.D.Cicero
compound source
Molecule: Regulatory Protein E2
Chain: A, B
Fragment: Dna-Binding Domain
Synonym: Hpv-16 E2 Trascription Factor
Engineered: Yes
Organism_scientific: Human Papillomavirus Type 16
Organism_common: Viruses
Gene: E2
Expression_system: Escherichia Coli
Expression_system_common: Bacteria
Expression_system_strain: Jm109
Expression_system_vector_type: Plasmid
Expression_system_plasmid: Ptz18u-E2
methodNMR
Gene E2 (H. papillomavirus)
Gene
Ontology
ChainFunctionProcessComponent
A, B
  • nucleotide binding
  • DNA binding
  • transcription factor activit...
  • DNA replication
  • regulation of DNA replicatio...
  • transcription
  • regulation of transcription,...
  • viral reproduction
  • nucleus
  • host cell nucleus
  • Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (52 Kb) [Save to disk]
  • Biological Unit Coordinates (1zzf.pdb1.gz) 51 Kb
  • CSU: Contacts of Structural Units for 1ZZF
  • Original NMR restraints for 1ZZF from PDB
  • Experimental data, such as chemical shifts, at BioMagResBank (BMRB)
  • NMR Restraints Grid from BioMagResBank (BMRB)
  • Retrieve 1ZZF in mmCIF format [Save to disk]
  • View 1ZZF in 3D
  • Proteopedia, because life has more than 2D.
  • On Jmol, a nice Rasmol like molecule viewer. This is good for easiest viewing of basic structure.
  • On FirstGlance, an excellent tool for a guided tour on the structure components, by E. Martz.
  • On AstexViewer, from MSD-EBI (viewer documentation).
  • On RasMol (Install RasMol freeware) Here's help on how to use RasMol.
  • Visual 3D analysis of 1ZZF
  • Protein Explorer, Easier to use and more powerful than RasMol. (Win and Mac only)
  • Noncovalent Bond Finder displays the closest contacts to ligand or interface, reports distances, walks over water bridges.
  • Cartoon representation from PDB Cartoon
  • Ramachandran plot from PDBSum
  • Structure-derived information
  • Dipole moment, from Dipole Server at Weizmann Institute
  • Crystal Contacts, from CryCo at Weizmann Institute
  • 3D motif for 1ZZF, from MSDmotif at EBI
  • Fold representative 1zzf from FSSP and Dali (Families of Structurally Similar Proteins)
  • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [1zzf_B] [1zzf_A]
  • Other resources with information on 1ZZF
  • MMDB (Entrez's Structure Database)
  • Movements, Movies and Images
  • Images from IMB Jena Image Library of Biological Macromolecules.

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