2FJC Metal Transport date Jan 02, 2006
title Crystal Structure Of Antigen Tpf1 From Treponema Pallidum
authors A.Thumiger, A.Polenghi, E.Papinutto, R.Battistutta, C.Montecucco, G.Zanotti
compound source
Molecule: Antigen Tpf1
Chain: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Synonym: Antigen C1-5, Antigen 4d
Engineered: Yes
Organism_scientific: Treponema Pallidum
Organism_common: Bacteria
Gene: Tpf1
Expression_system: Escherichia Coli
Expression_system_common: Bacteria
Expression_system_strain: Xl 1blue
Expression_system_vector_type: Plasmid
Expression_system_plasmid: Psm214g-Tpf1
symmetry Space Group: P 3 2 1
R_factor 0.227
crystal
cell
length a length b length c angle alpha angle beta angle gamma
184.921 184.921 154.883 90.00 90.00 120.00
method X-Ray Diffractionresolution 2.50 Å
ligand FE enzyme
note 2FJC is a representative structure
similarity Belongs to the dps family.[Ferritin]
subunit Homodecamer; either linked or stabilized by disulfide bonds.
Gene TPF1 (T. pallidum); TP (T. pallidum)
function May play an important structural role in the outer membrane.
Gene
Ontology
ChainFunctionProcessComponent
F, N, K, E, M, C, L, A, J, O, P, B, H, D, I, G
  • ferric iron binding
  • oxidoreductase activity
  • transition metal ion binding...
  • cellular iron ion homeostasi...
  • response to stress

  • Primary referenceCrystal structure of antigen TpF1 from Treponema pallidum., Thumiger A, Polenghi A, Papinutto E, Battistutta R, Montecucco C, Zanotti G, Proteins. 2005 Dec 12;. PMID:16345079
    Data retrieval
  • Asymmetric unit, PDB entry: [header only] [complete with coordinates] (393 Kb) [Save to disk]
  • Biological Unit Coordinates (2fjc.pdb1.gz) 294 Kb
  • Biological Unit Coordinates (2fjc.pdb2.gz) 285 Kb
  • CSU: Contacts of Structural Units for 2FJC
  • Likely Quarternary Molecular Structure file(s) for 2FJC
  • Structure Factors (918 Kb)
  • Retrieve 2FJC in mmCIF format [Save to disk]
  • View 2FJC in 3D
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  • Structure-derived information
  • Electron Density related parameters from EDS Electron Density Server, at Upsala
  • Dipole moment, from Dipole Server at Weizmann Institute
  • Crystal Contacts, from CryCo at Weizmann Institute
  • 3D motif for 2FJC, from MSDmotif at EBI
  • Fold representative 2fjc from FSSP and Dali (Families of Structurally Similar Proteins)
  • Sequence-derived information
  • View one-letter amino acid or nucleotide sequence for each chain: [2fjc_C] [2fjc_K] [2fjc_B] [2fjc_E] [2fjc_L] [2fjc_F] [2fjc_G] [2fjc_D] [2fjc_A] [2fjc_N] [2fjc_H] [2fjc_P] [2fjc_J] [2fjc_I] [2fjc_O] [2fjc_M]
  • Other resources with information on 2FJC
  • InterPro: IPR012347 , IPR002177 , IPR008331
  • PDBREPORT (protein verification by WHAT_CHECK procedures)
  • MMDB (Entrez's Structure Database)
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