2O0I	Surface Active Protein	date	Nov 27, 2006
title	Crystal Structure Of The R185a Mutant Of The N-Terminal Domain Of The Group B Streptococcus Alpha C Protein
authors	J.M.Hogle, D.J.Filman, M.J.Baron, L.C.Madoff, A.Iglesias
compound		source
Molecule: C Protein Alpha-Antigen Chain: 1 Fragment: N-Terminal Domain, Residues 57-227 Engineered: Yes Mutation: Yes		Organism_scientific: Streptococcus Agalactiae Serogroup Ia Organism_common: Bacteria Strain: Strain A909 Gene: Bca Expression_system: Escherichia Coli Expression_system_common: Bacteria Expression_system_strain: Bl21(De3) Expression_system_vector_type: Plasmid Expression_system_plasmid: Pet24a
symmetry	Space Group: P 61 2 2	R_factor	0.245
crystal cell	length a length b length c angle alpha angle beta angle gamma 55.700 55.700 277.940 90.00 90.00 120.00
method	X-Ray Diffraction	resolution	3.10 Å
Gene	BCA (S. agalactiae); SAK (S. agalactiae)
Gene Ontology	Chain Function Process Component 1 pathogenesis cell wall cell surface membrane
Primary reference	Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B streptococci into host cells., Baron MJ, Filman DJ, Prophete GA, Hogle JM, Madoff LC, J Biol Chem. 2007 Apr 6;282(14):10526-36. Epub 2007 Jan 26. PMID:17259175

Data retrieval

Asymmetric unit, PDB entry: [header only] [complete with coordinates] (32 Kb) [Save to disk] Biological Unit Coordinates (2o0i.pdb1.gz) 28 Kb CSU: Contacts of Structural Units for 2O0I Likely Quarternary Molecular Structure file(s) for 2O0I Structure Factors (40 Kb) Retrieve 2O0I in mmCIF format [Save to disk]

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Structure-derived information

Electron Density related parameters from EDS Electron Density Server, at Upsala Dipole moment, from Dipole Server at Weizmann Institute Crystal Contacts, from CryCo at Weizmann Institute 3D motif for 2O0I, from MSDmotif at EBI Fold representative 2o0i from FSSP and Dali (Families of Structurally Similar Proteins)

Sequence-derived information

View one-letter amino acid or nucleotide sequence for each chain: [2o0i_1]

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