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B-cell epitope prediction


Bcepred (www.imtech.res.in/raghava/bcepred) The aim of this server is to predict B cell epitope regions in an antigen sequence, using physico-chemical properties.
Bcepred has been tested on B cell epitope database, BCIPEP (www.imtech.res.in/raghava/bcipep), and will therefore presumbly have better performance for prediction of B cell epitope of an antigen. Bcepred can predict continuous B cell epitopes. Identified properties of B cell epitope includes hydrophilicity, flexibility/mobility, accessibility, polarity, exposed surface and turns. Quantification of these properties is determined by assigning a value to each of the 20 natural amino acids.

ABCpred (www.imtech.res.in/raghava/abcpred) The aim of ABCpred server is to predict linear B cell epitope regions in an antigen sequence, using artificial neural network.
Users can select window length of 10, 12, 14, 16 and 20 as predicted epitope length. It presents the results in graphical and tabular frame. In case of graphical frame, this server plot the epitopes in blue color along protein backbone (black color), which assist the users in rapid visulaziation of B-cell epitope on protein. The tabular output is in the form of a table, which will provide the aminoacids length from N-terminal to C-terminal in a protein predicted by the server.

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