================================== Hybrid Approach1 [Composition and PROSITE] Based ===================================== Prediction between Amino Acyl tRNA Synthetases and Non Amino Acyl tRNA Synthetases Redundancy Positive Negative Sensitivity Specificity Accuracy MCC Threshold Sequences Sequences (%) (%) (%) 100% 9889 9889 96.64 97.15 96.90 0.94 0.1 90% 6487 6487 95.55 96.01 95.78 0.92 0.1 80% 4998 4998 95.80 93.26 94.53 0.89 0.0 70% 3686 3686 94.82 92.67 93.75 0.88 0.0 60% 2369 2369 92.44 91.89 92.17 0.84 0.0 50% 1330 1330 90.75 90.60 90.68 0.81 0.0 40% 669 669 94.02 83.26 88.64 0.78 -0.2 30% 117 117 80.36 79.64 79.93 0.60 0.0 ************************************************************************************************************************ Prediction between Amino Acyl tRNA Synthetases Class 1 and Amino Acyl tRNA Synthetases Class 2 Redundancy Positive Negative Sensitivity Specificity Accuracy MCC Threshold Sequences Sequences (%) (%) (%) 100% 4346 5547 99.70 99.05 99.33 0.99 0.0 90% 2939 3551 99.59 98.79 99.15 0.98 0.0 80% 2305 2695 99.48 98.74 99.08 0.98 0.0 70% 1750 1938 99.31 98.30 98.78 0.98 0.0 60% 1157 1214 98.62 97.61 98.10 0.96 0.0 50% 666 666 97.74 95.94 96.85 0.94 0.0 40% 346 325 93.35 95.38 94.34 0.89 0.1 30% 53 65 81.09 83.08 82.18 0.65 0.1 ************************************************************************************************************************