Server
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Description
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ProPred1:
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The
aim of this server is to predict MHC Class-I binding regions in an antigen
sequence (Singh, H. and Raghava, G.P.S. (2003) Bioinformatics, 19: 1009)
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ProPred:
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The
aim of this server is to predict MHC Class-II binding regions in an antigen
sequence (Singh, H. and Raghava, G. P. S. (2001) Bioinformatics 17: 1236)
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BcePred:
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The
BcePred server predict B cell epitope based on physio-chemical properties of
amino acids. (Saha,S and Raghava GP (2004) ICARIS, LNCS 3239,197-204)
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nHLAPred:
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This
server allow to predict binding peptide for 67 MHC Class I alleles. This also
allow to predict the proteasome cleavage site and binding peptide that have
cleavage site at C terminus (potential T cell epitopes). This uses the hybrid
approach for prediction (Neural Network + Quantitative Matrix)
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HLADR4Pred:
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SVM
and ANN based methods for predicting HLA-DRB1*0401 binding peptides in an
Antigen Sequence (Bhasin, M. and Raghava, G.P.S. (2003) Bioinformatics
20:421).
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ABCpred:
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ABCpred
server is to predict linear B cell epitope regions in an antigen sequence, using
artificial neural network. This server will assist in locating epitope
regions that are useful in selecting synthetic vaccine candidates, disease
diagonosis and also in allergy research. ( Saha, S. and Raghava, G. P. S.
(2006) PROTEINS:Structure, Function, and Bioinformatics (In Press) )
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MMBPred
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Prediction
of of MHC class I binders which can bind to wide range of MHC alleles with
high affinity. This server has potential to develop sub-unit vaccine for
large population (Bhasin, M., and Raghava, G.P.S. (2003) Hybridoma and
Hybridomics 22: 229)
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MHC2Pred:
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Prediction
of binders for MHC class II alleles. This allows to predict promiscuous class binders, which can bind
to large number of MHC Class II alleles.
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Bcipep:
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Bcipep
is a collection of the peptides having the role in Humoral immunity. The
peptides in the database has varying measure of immunogenicity.This database can
assist in the development of method for predicting B cell epitopes,
desigining synthetic vaccines and in disease diagnosis. This databse is also
launched by European Bioinformatics Institute (EBI) Hinxton, Cambridge, UK. (Saha S, Bhasin M, Raghava GP. (2005) BMC Genomics. 6(1):79)
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Pcleavage:
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This
server allows server to predict
proten (Immuno and standard) (Bhasin M, Raghava GP. (2005) Nucleic Acids Res.33(Web Server
issue):W202-7)
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MHC
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Matrix Optimization Technique for Predicting
MHC binding Core (Singh, H. and Raghava, G. P. S. (2002) Biotech Software
and Internet Report, 3:146)
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HLAPRED:
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A
server for predicting binders for MHC class I and II alleles. It also search
these predicted binders in various genomes.
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TAPPred:
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TAPPred
is an on-line service for predicting binding affinity of peptides toward the
TAP transporter. The Prediction is based on cascade SVM, using sequence and
properties of the the amino acids (Bhasin, M. and Raghava, G. P. S. (2004)
Protein Science 13:596-607).
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MHCBench :
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It is an interface developed for evaluating the Major
Histocompatibility Complex (MHC) binding peptide prediction algorithms.
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MHCBN:
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The
MHCBN is a curated database consisting of detailed information about Major
Histocompatibility Complex (MHC) Binding,Non-binding peptides and T-cell
epitopes.The version 3.1 of database provides information about peptides interacting
with TAP and MHC linked autoimmune diseases This databse is also launched by
European Bioinformatics Institute (EBI) Hinxton, Cambridge, UK. (Bhasin,
M., Singh, H. and Raghava, G. P. S. (2003) Bioinformatics 19: 665).
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CTLPred:
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Direct
method of prediction of CTL Epitopes in an antigen sequence. This server
utlize the machine learning techniques Support Vector Machine(SVM) and
Aritificial Neural Network (ANN) for prediction (Bhasin, M. and Raghava,
G. P. S. (2004) Vaccine 22:3195-204
)
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Ab/Ag concentartion
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This
web-server allow to compute the endpoint titer and concentration of
Antibody(Ab) or Antigen(Ag) from ELISA data(Raghava, G. P. S. and Agrewala,
J. N. (2001) Biotech Software and Internet Report, 2:196). This server is
based on graphical method developed for calculating Ab/Ag concentration (Raghava,
G.P.S., Joshi, A.K. and Agrewala, J.N. (1992) J. Immunol. Methods 153,
263-264).
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HaptenDB:
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A
database of hapten molecules which
can not activate immune system but can stimulate immune response if attach
with the carrier proteins. (Singh, M.K., Srivastava, S.,Raghava, G. P. S. and Varshney, G.C.
(2006) Bioinformatics 22:253-5.)
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HLA_affi:
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This is a SVM based server developed for predicting the binding affinity of peptides binding to HLA-A2 allele
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FDR4:
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This server predicts the binding core and binding affinity of peptides binding to HLA-DRB1*0401 allele
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