Virtual Scanning of Toxic Peptides

This tool allows the users to identify highly toxic or non-toxic peptides from large number peptides submitted by a user. It predict their toxicity along with all the important physico-chemical properties like hydrophobicity, charge pI etc. of peptides submitted by users. To generate mutants of specific peptide, user need to click on the peptide. For more information click Help.


Type or paste peptide sequence(s) in single letter code (in FASTA format):

     OR     Submit sequence file:  

Either select SVM method: SVM (Swiss-Prot) based   SVM (Swiss-Prot) + Motif based   SVM (TrEMBL) based   SVM (TrEMBL) + Motif based      

OR

Select Quantitative Matrix (QM) method: Monopeptide(Swiss-Prot)   Monopeptide (TrEMBL)  Dipeptide (Swiss-Prot)   Dipeptide (TrEMBL)      

Choose E-value cut-off for motif-based method:    

Choose SVM threshold:    

Physicochemical Properties to Be Displayed:
 Hydrophobicity     Sterichinderance     Side bulk     Hydropathicity     Amphipathicity     Hydrophilicity     Net Hydrogen   
 Charge  pI     Molecular weight  All