ID |
Reference |
Source Clone name |
Sequence |
Motif |
Target-tumor |
Target-cell |
Receptors-biomarker |
Phage/Library |
In vitro/Ex-vivo |
In vivo |
Homing/targeting |
Payloads |
patent |
1017 | Liu S et al. Acta Pharmacol Sin. 2011 Jan;32(1):79-88. | Bombesin | QRLGNQWAVGHLM | NA | Lung, gastric cancer, Neuroblastoma | NA | NA | NA | MCF-7, DU145, A375 HeLa, A875, M14, A549, ZR-75-30, Raji, NB4, K562 cell lines | Eight-week-old female nude mice with MCF-7 xenograft | Homing | MG2 peptide | NA |
1152 | Hu S et al. Biochem Biophys Res Commun. 2006 Mar 24;341(4):964-72. | peptide 20 | GRRTRSRRLRRS | NA | Gastric cancer, Liver metastassis | Tumor cell | NA | M13PIII phage/12 mer random peptide library | Human gastric cancer cell line XGC9811, XGC9811(liver metastatic gastric cell line) LAGS, MKN45 | BALB/c nude mice( 4- to 5-weeks-old) bearing human gastric carcinoma cell line XGC9811 xenograft | Homing | NA | NA |
1153 | Hu S et al. Biochem Biophys Res Commun. 2006 Mar 24;341(4):964-72. | Phage 1, 3, 6 | SMSIASPQIPWS | NA | Gastric cancer, Liver metastassis | Tumor cell | NA | M13PIII phage/12 mer random peptide library | Human gastric cancer cell line XGC9811, XGC9811(liver metastatic gastric cell line) LAGS, MKN45 | BALB/c nude mice( 4- to 5-weeks-old) bearing human gastric carcinoma cell line XGC9811 xenograft | Homing (Phage display clone) | NA | NA |
1154 | Hu S et al. Biochem Biophys Res Commun. 2006 Mar 24;341(4):964-72. | Phage 2, 4, 10, 23 | TPRNLRTSNTHR | NA | Gastric cancer, Liver metastassis | Tumor cell | NA | M13PIII phage/12 mer random peptide library | Human gastric cancer cell line XGC9811, XGC9811(liver metastatic gastric cell line) LAGS, MKN45 | BALB/c nude mice( 4- to 5-weeks-old) bearing human gastric carcinoma cell line XGC9811 xenograft | Homing (Phage display clone) | NA | NA |
1155 | Hu S et al. Biochem Biophys Res Commun. 2006 Mar 24;341(4):964-72. | Phage 5, 11, 15, 19, 25 | GRRIAGPYIALE | NA | Gastric cancer, Liver metastassis | Tumor cell | NA | M13PIII phage/12 mer random peptide library | Human gastric cancer cell line XGC9811, XGC9811(liver metastatic gastric cell line) LAGS, MKN45 | BALB/c nude mice( 4- to 5-weeks-old) bearing human gastric carcinoma cell line XGC9811 xenograft | Homing (Phage display clone) | NA | NA |
1156 | Hu S et al. Biochem Biophys Res Commun. 2006 Mar 24;341(4):964-72. | Phage 7, 9, 13, 18 | SMPINSPYIPWS | NA | Gastric cancer, Liver metastassis | Tumor cell | NA | M13PIII phage/12 mer random peptide library | Human gastric cancer cell line XGC9811, XGC9811(liver metastatic gastric cell line) LAGS, MKN45 | BALB/c nude mice( 4- to 5-weeks-old) bearing human gastric carcinoma cell line XGC9811 xenograft | Homing (Phage display clone) | NA | NA |
1157 | Hu S et al. Biochem Biophys Res Commun. 2006 Mar 24;341(4):964-72. | Phage 8, 16 | GRRPMKLNKTP | NA | Gastric cancer, Liver metastassis | Tumor cell | NA | M13PIII phage/12 mer random peptide library | Human gastric cancer cell line XGC9811, XGC9811(liver metastatic gastric cell line) LAGS, MKN45 | BALB/c nude mice( 4- to 5-weeks-old) bearing human gastric carcinoma cell line XGC9811 xenograft | Homing (Phage display clone) | NA | NA |
1158 | Hu S et al. Biochem Biophys Res Commun. 2006 Mar 24;341(4):964-72. | Phage 12, 14, 17 | GRRINRLILPRN | NA | Gastric cancer, Liver metastassis | Tumor cell | NA | M13PIII phage/12 mer random peptide library | Human gastric cancer cell line XGC9811, XGC9811(liver metastatic gastric cell line) LAGS, MKN45 | BALB/c nude mice( 4- to 5-weeks-old) bearing human gastric carcinoma cell line XGC9811 xenograft | Homing (Phage display clone) | NA | NA |
1159 | Hu S et al. Biochem Biophys Res Commun. 2006 Mar 24;341(4):964-72. | Phage 27, 28 | GRRTRSSRLRNS | NA | Gastric cancer, Liver metastassis | Tumor cell | NA | M13PIII phage/12 mer random peptide library | Human gastric cancer cell line XGC9811, XGC9811(liver metastatic gastric cell line) LAGS, MKN45 | BALB/c nude mice( 4- to 5-weeks-old) bearing human gastric carcinoma cell line XGC9811 xenograft | Homing (Phage display clone) | NA | NA |
1167 | Zhi M et al. Cancer Biol Ther. 2004 Dec;3(12):1232-5. | NA | CGNSNPKSC | NA | Gastric cancer | Endothelial cell | NA | T7 phage/C7C peptide library | Human umbilical vein endothelial cells( HUVEC), lovo cells, Hep-g2 cells, SGC-7901 cells, Eca-109 cells | 2 month old Balb/c mice of human xenograft of gastric cancer | Homing | NA | NA |
1168 | Zhi M et al. Cancer Biol Ther. 2004 Dec;3(12):1232-5. | NA | CPHNLTKLC | NA | Gastric cancer | Endothelial cell | NA | T7 phage/C7C peptide library | Human umbilical vein endothelial cells( HUVEC), lovo cells, Hep-g2 cells, SGC-7901 cells, Eca-109 cells | 2 month old Balb/c mice of human xenograft of gastric cancer | Homing (Phage display clone) | NA | NA |
1359 | Chen B et al. BMC Cell Biol. 2009 Sep 9;10:63. | GX1 | CGNSNPKSC | NA | Gastric cancer | Endothelial cell | NA | NA | HUVEC cultured in tumor-conditioned medium,Gastric cancer cell line SGC7901 | Nude mice | Homing | GX1-rmhTNF alpha labeled with 99TcmO4, Antitumor cytokine rmhTNF alpha | CN1580075, CN1872880 |
1391 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | Peptide PIII | SMSIASPYIALE | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | 6-week-old BALB/C bearing of GC9811 xenograft | Homing | NA | NA |
1392 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | PI | SMSIASPYIPWS | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | NA | Targeting | NA | NA |
1393 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | PII | SPGPMKLLKTPL | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | NA | Targeting | NA | NA |
1394 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | PIV | TLNINRLILPRT | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | NA | Targeting | NA | NA |
1395 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | PV | SMSIGSPYITFG | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | NA | Targeting | NA | NA |