| ID |
Reference |
Source Clone name |
Sequence |
Motif |
Target-tumor |
Target-cell |
Receptors-biomarker |
Phage/Library |
In vitro/Ex-vivo |
In vivo |
Homing/targeting |
Payloads |
patent |
| 1166 | Zurita AJ et al. Cancer Res. 2004 Jan 15;64(2):435-9. | NA | CGRRAGGSC | NA | Prostate cancer | Tumor cell | IL-11 receptor | NA | Human primary and metastatic prostate cancer samples,cancer-derived cell lines MDA-PCa-2b and LNCaP | NA | Targeting | NA | WO0402020722A2 |
| 1262 | Chen Y et al. Cancer Res. 2001 Mar 15;61(6):2434-8. | NA | CRGDCGGKWCFRVCYRGICYRRCR | RGD | Prostate cancer, Melanoma | Tumor cell and Endothelial cell | Integrins | NA | The TSU human prostate cancer cells, B16 melanoma, nontumorigenic cell lines Cos-7, and NIH-3T3 | CAMs of 10-day-old chicken embryos, C57BL/6 mice bearing B16 melanoma | Homing | Antimicrobial peptide | NA |
| 1324 | Teesalu T et al. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16157-62. | NA | RPARPAR | RXXR | Human prostate carcinoma | Parenchyma cell | NA | T7 phage/ cyclic CX7C. library linear X7 peptide library | NA | PPC-1 human prostate carcinoma xenograft tumors | Homing | Quantum dots | US 2009/0246133 A1 |
| 1328 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKGPDC | RGD | Prostate, Pancreatic ductal, breast cancer, bone , brain, cervical cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | Nude mice with multiple tumors (prostrate PC-3, PPC1, 22RVI Xenograft), (pancreatic MIAPaCa-2 Xenograft) | Homing | Iron oxide nanoworms, iRGD-linked abraxane | US 2009/0246133A1 |
| 1329 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDRGPDC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | NA |
| 1330 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKTTNC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | NA |
| 1331 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDHAGDC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | NA |
| 1332 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDHGVEC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1333 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGRGDNLPC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1334 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGRGDNLAC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1335 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CEKRGDNLC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1336 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CEKRGDSVC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1337 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CSGRGDSLC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1338 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGKRGDSIC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1339 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CTGRGDALC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1340 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDSAC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1341 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKGENC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1342 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGRGDSPDC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1343 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKGPEC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1344 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKHADC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1345 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDHAANC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1346 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDAGINC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1347 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGRGDMPSC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1348 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CEKRGDSLC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
| 1373 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | PC5-52 | SVSVGMKPSPRP | PSP | Lung and Prostate cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice human cancers including human lung (H460), colon (HCT116), breast (BT483), prostate (PC3), liver (Mahlavu), and pancreatic (PaCa) cancer xenografts | Homing | Doxorubicin | US/ 20100119444A1,US 2010/0260673A1 |
| 1402 | Zitzmann S et al. Clin Cancer Res. 2005 Jan 1;11(1):139-46. | DUP-1 peptide | FRPNRAQDYNTN | NA | Prostate carcinomas | NA | Prostate-specific membrane antigen | M13 phage /12 mer peptide library | Prostate-specific membrane antigen–negative cell line DU-145 ,HUVEC | Male 6-week-old BALB/c mice and Copenhagen rats weighing 220 to 250 g | Homing | Radioisotope131 | NA |
| 1467 | Dharap SS et al. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12962-7. | NA | QHWSYKCIRP | NA | Ovarian, breast, and prostate cancer | NA | LHRH(Receptors for luteinizing hormone-releasing hormone) | NA | The human ovarian carcinoma A2780 cell line | Mice bearing xenografts of human ovarian carcinoma.female athymic nude mice | Homing | Radiolabeled with tritium (CPT-PEG-LHRH conjugate) | NA |
| 1694 | NA | Clone1 | WQPDTAHHWATL | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | FITC | US 2009/0274625A1 |
| 1695 | NA | Clone 2 | HNAYWHWPPSMT | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | Phage ELISA on his tagged PSMA | NA | Targeting | NA | US 2009/0274625A1 |
| 1696 | NA | Clone 3 | GHLIPLRQPSH | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1697 | NA | Clone 4 | YTSPHHSTTGHL | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1698 | NA | Clone 5 | WTHHHSYPRPL | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1699 | NA | Clone 6 | NSFPLMLMHHHP | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1700 | NA | Clone 7 | KHMHWHPPALN | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1701 | NA | Clone 8 | SLDSMSPQWHAD | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1702 | NA | Clone 9 | SEFIHHWTPPPS | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1703 | NA | Clone 10 | NGFSHHAPLMRY | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1704 | NA | Clone 11 | HHEWTHHWPPP | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1705 | NA | Clone 12 | AWPENPSRRPF | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1706 | NA | Clone 13 | AGFQHHPSFYRF | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1707 | NA | Clone 17 | QRSPMMSRIRLP | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1708 | NA | Clone 15 | YRHWPIDYPPP | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | The LNCaP, PC-3 and DU-145 human prostate cancer cell lines | NA | Targeting | NA | US 2009/0274625A1 |
| 1709 | NA | Clone 16 | MIHTNHWWAQD | NA | Prostate cancer | NA | PSMA, Prostrate specific membrane antigen | M13 phage /12mer peptide library | Phage ELISA on his tagged PSMA | NA | Targeting | NA | US 2009/0274625A1 |
| 1720 | NA | NA | CSMSAKKKC | NA | Prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1721 | NA | NA | CKTRVSCGV | NA | Prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1722 | NA | NA | CASLSCR | NA | Prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1723 | NA | NA | CSGGKVLDC | NA | Prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1724 | NA | NA | CASLSCR | NA | Premalignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1725 | NA | NA | CSGGKVLDC | NA | Premalignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1726 | NA | NA | CSMSAKKKC | NA | Malignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1727 | NA | NA | CKTRVSCGV | NA | Malignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1728 | NA | NA | CASLSCR | NA | Malignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1729 | NA | Clone 6 | WIFPWIQL | NA | Prostate cancer | NA | NA | Phage /CX3-10C peptide library | Human prostate cancer-derived cell lines MDA-PCa-2b and LNCaP | Athymic nude mice bearing size-matched human DU 145 xenografts | Homing | Apoptotic peptide (KLAKLAK) | US 2005/0191294A1 |
| 1730 | NA | Clone 11 | WDLAWMFRLPVG | NA | Prostate cancer | NA | NA | Phage /CX3-10C peptide library | Human prostate cancer-derived cell lines MDA-PCa-2b and LNCaP | Athymic nude mice bearing size-matched human DU 145 xenografts | Homing | Apoptotic peptide (KLAKLAK) | US 2005/0191294A1 |
| 1731 | NA | Clone 2 | CRGSGAGRC | NA | Prostate cancer | NA | NA | Phage /CX3-10C peptide library | Human prostate cancer-derived cell lines MDA-PCa-2b and LNCaP | Athymic nude mice bearing size-matched human DU 145 xenografts | Homing | Apoptotic peptide (KLAKLAK) | US 2005/0191294A1 |
| 1732 | NA | Clone 4 | CKGGRAKDC | NA | Prostate cancer | NA | NA | Phage /CX3-10C peptide library | Human prostate cancer-derived cell lines MDA-PCa-2b and LNCaP | Athymic nude mice bearing size-matched human DU 145 xenografts | Homing | Apoptotic peptide (KLAKLAK) | US 2005/0191294A1 |
| 1733 | NA | Clone 5 | CGSPGWVRC | NA | Prostate cancer | NA | NA | Phage /CX3-10C peptide library | Human prostate cancer-derived cell lines MDA-PCa-2b and LNCaP | Athymic nude mice bearing size-matched human DU 145 xenografts | Homing | Apoptotic peptide (KLAKLAK) | US 2005/0191294A1 |
| 1745 | Tan M et al. Pharma Res 2011 Dec 3. | CLT1 | CGLIIQKNEC | NA | Prostate cancer | Fibrillar meshwork in the extracellular compartment of the tumors | NA | NA | PC-3 human prostate adenocarcinoma cells | Athymic male nude mice | Homing | Gadolinium-tetraazacyclododecanetetraacetic acid (Gd-DOTA) complex | US 2009/021442A1 |
| 1752 | Hatakeyama S et al. Proc Natl Acad Sci U S A.2011 Dec 6;108(49):19587-92. | IF7 | IFLLWQR | NA | Lung carcinoma, Prostate cancer, Breast Cancer, Colon cancer | Tumor vessel | Anxa1 | NA | NA | Nude mice bearing HCT116 tumors,C57BL6 mice bearing B16F1 and Lewis lung carcinoma,SCID mice bearing prostate tumor | Homing | Alexa 488 (A488), Drug SN-38 , 17-AAG (GA), a geldanamycin analogue | US 7,470,658 B2 |
| 1759 | Ito T et al. Bioorg Med Chem Lett 2011 Jun 15;21(12):3515-8. | c(RGDfK) peptide | RGDfK | NA | Human glioblastoma and prostate cancer | NA | Integrins | NA | U87 - MG cells, PC3 cells | NA | Targeting | Lanthanide complexes | US 2003/0125243 A1 |