| ID |
Reference |
Source Clone name |
Sequence |
Motif |
Target-tumor |
Target-cell |
Receptors-biomarker |
Phage/Library |
In vitro/Ex-vivo |
In vivo |
Homing/targeting |
Payloads |
Patent |
| 1373 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | PC5-52 | SVSVGMKPSPRP | PSP | Lung and Prostate cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice human cancers including human lung (H460), colon (HCT116), breast (BT483), prostate (PC3), liver (Mahlavu), and pancreatic (PaCa) cancer xenografts | Homing | Doxorubicin | US/ 20100119444A1,US 2010/0260673A1 |
| 1374 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | PC5-54 | WPLHTSVYPPSP | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing | NA | US 2008/0193510A1 |
| 1375 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-5 | NTLPPFSPPSPP | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1376 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-10 | SFPDSNIAPSSP | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1377 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-8 | QHAPSNSKSVLT | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1378 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-7 | WPTYLNPSSLKA | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1379 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-57 | GPSGNLHIRPAS | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1380 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-53 | SPLLSTRAVQLS | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1381 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-58 | SPMFTMIQGDAQ | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1382 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-60 | VNSHQALWSPAQ | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1383 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-4 | STLPPPLRFANV | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | US 2008/0193510A1 |
| 1384 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-2 | SFNQPYLYKTAF | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1385 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-3 | YHTRIALPDNLP | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1386 | Lee TY et al. Cancer Res. 2007 Nov 15;67(22):10958-65. | Clone PC5-11 | AQSTAFQKPLLM | NA | Lung cancer | Tumor vessel | Integrins, Alpha-5 beta-3 and Alpha-5 beta-5 | M13 phage/random peptide library | CL1-5 (lung cancer), H460 (lung cancer) ,PC-3 (prostate cancer),VEGF-stimulated HUVECs and human lung cancer vessels | SCID mice with lung cancer xenograft | Homing (Phage display clone) | NA | NA |
| 1387 | Kumar SR et al. Clin Cancer Res. 2007 Oct 15;13(20):6070-9. | NA | KCCYSL | NA | Human breast carcinoma | Tumor cell | ErbB-2 | NA | MDA-MB,Human breast carcinoma cell line, Prostate carcinoma cell line (PC-3),K-562 human erythroid leukemia cell line | SCID mice, MDA-MB-435 breast carcinoma cell | Homing | 111In-DOTA, Biotin | US 2010/0061930 |
| 1389 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CSDSWHYWC | NA | Colon cancer | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3 ) | M13 phage / 7-mer peptide library | The human colon cancer cell line (HT29),Human umbilical vein endothelial cell line (EVC304),Human retinoblastoma cell line (Y79), Human amino cell line (WISH),Human hepatic cancer cell line (HepG2),Human alveolar epithelial cell line (A549) | NA | Targeting | FITC | US 2010/0233161 |
| 1390 | Zhang B et al. Mol Med. 2007 May-Jun;13(5-6):246-54. | Synthetic peptide HCBP1 | FQHPSFI | NA | Hepatoma cancer | Tumor cell | NA | M13 phage /7- mer peptide library | Hepatocellular carcinoma cell line (HepG2),Hepatocellular carcinoma cell line (HepG2),Normal hepatocyte line (L-02) ,The hepatocellular carcinoma cell lines and BEL-7402, Passage cell line of human cervical cancer Hela,Human patients biopsies | Balb-c mice bearing HepG2 xenografts | Homing | FITC | NA |
| 1391 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | Peptide PIII | SMSIASPYIALE | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | 6-week-old BALB/C bearing of GC9811 xenograft | Homing | NA | NA |
| 1392 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | PI | SMSIASPYIPWS | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | NA | Targeting | NA | NA |
| 1393 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | PII | SPGPMKLLKTPL | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | NA | Targeting | NA | NA |
| 1394 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | PIV | TLNINRLILPRT | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | NA | Targeting | NA | NA |
| 1395 | Bai F et al. J Mol Med (Berl). 2007 Feb;85(2):169-80. | PV | SMSIGSPYITFG | NA | Gastric cancer | NA | NA | M13 phage/12 mer peptide library | Novel cell line, GC9811-P,Human gastric cancer cell lines, SGC7901, Human gastric cancer cell lines AGS, Human gastric cancer cell lines MKN45 ,Immortal gastric epithelial cells, GES-1, GC9811 | NA | Targeting | NA | NA |
| 1396 | Maruta F et al. J Drug Target. 2007 May;15(4):311-9. | NA | VPNTNSLPAAVN | TNSLP | Human colorectal tumor | Tumor vessel | NA | M13 phage/12-mer linear peptide library | Human colorectal cancer biopsies | NA | Targeting | NA | NA |
| 1397 | Maruta F et al. J Drug Target. 2007 May;15(4):311-9. | NA | LIAKTALPQTNK | AxPxTN | Human colorectal tumor | Tumor vessel | NA | M13 phage/12-mer linear peptide library | Human colorectal cancer biopsies | NA | Targeting | NA | NA |
| 1399 | Maruta F et al. J Drug Target. 2007 May;15(4):311-9. | NA | LIAKTALPQTN | AxPxTN | Human colorectal tumor | Tumor vessel | NA | M13 phage/12-mer linear peptide library | Human colorectal cancer biopsies | NA | Targeting | NA | NA |
| 1400 | Zhao X et al. J Exp Clin Cancer Res. 2007 Dec;26(4):509-14. | NA | CPHSKPCLC | NA | Human colon cancer | Endothelial cells | NA | Phage/7-mer peptide library. | Human umbilical vein endothelial cells (HUVEC), Gastric cancer cell line ,Esophageal cancer cells, Colon cancer cells, Liver cancer cells | BALB/C mice with colon cancer xenograft | Homing | NA | NA |
| 1401 | Borgne-Sanchez A et al. Cell Death Differ. 2007 Mar;14(3):422-35. | TEAM-VP | GGCRGDMFGC | RGD | Metastiasis in tumor | Angiogenic endothelial cells | Alpha-5 beta- 3 integrins | NA | HUVEC, HMVECd, A375M, MCF-7, MDA-MB-231, HeLa, HT-29, Jurkat, CEM and fresh peripheral blood mononuclear cells (PBMC) | BALB C mice | Homing | FITC, Apoptic peptide | WO96/15811,US 6,458,026 B1 |
| 1484 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | P1 | CSDSWHYWC | CSDxxHxWC | Colon cancer, Retinoblastoma | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | human VEGFR-2(hVEGFR-2) positive HT29 cell line and Y79 cell line | NA | Targeting | FITC | NA |
| 1485 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CSDWQHPWC | CSDxxHxWC | Tumor metastasis | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | ELISA assay on Human VEGFR-2(hVEGFR-2) ectodomain Fc fusion protein | NA | Targeting | NA | NA |
| 1486 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CSDYNHHWC | CSDxxHxWC | Tumor metastasis | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | ELISA assay on Human VEGFR-2(hVEGFR-2) ectodomain Fc fusion protein | NA | Targeting | NA | NA |
| 1487 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CSDGQHYWC | CSDxxHxWC | Tumor metastasis | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | ELISA assay on Human VEGFR-2(hVEGFR-2) ectodomain Fc fusion protein | NA | Targeting | NA | NA |
| 1488 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CYDSWHYWC | CSDxxHxWC | Tumor metastasis | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | ELISA assay on Human VEGFR-2(hVEGFR-2) ectodomain Fc fusion protein | NA | Targeting | NA | NA |
| 1489 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CFDGNHIWC | CSDxxHxWC | Tumor metastasis | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | ELISA assay on Human VEGFR-2(hVEGFR-2) ectodomain Fc fusion protein | NA | Targeting | NA | NA |
| 1490 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CTDFPRSFC | CSDxxHxWC | Tumor metastasis | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | ELISA assay on Human VEGFR-2(hVEGFR-2) ectodomain Fc fusion protein | NA | Targeting | NA | NA |
| 1491 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CTQDRQHPC | CSDxxHxWC | Tumor metastasis | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | ELISA assay on Human VEGFR-2(hVEGFR-2) ectodomain Fc fusion protein | NA | Targeting | NA | NA |
| 1492 | Qin X et al. J Biochem. 2007 Jul;142(1):79-85. | NA | CLSRYLDQC | CSDxxHxWC | Tumor metastasis | NA | VEGFR-3 (Human vascular endothelia growth factor receptor 3) | M13 phage /7 mer peptide library | ELISA assay on Human VEGFR-2(hVEGFR-2) ectodomain Fc fusion protein | NA | Targeting | NA | NA |
| 1498 | NA | NA | CGNKRTRGC | NA | Breast cancer | Lymphatic vessel | NA | T7 phage / random peptide library | MDA-MB-435 breast carcinoma cell line | HIFko tumor-bearing mice | Homing (Phage display clone) | NA | U.S. Pat. No. 7192921 |
| 1718 | NA | NA | CLSDGK | NA | Skin cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1719 | NA | NA | CLSDGKPVS | NA | Skin cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1720 | NA | NA | CSMSAKKKC | NA | Prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1721 | NA | NA | CKTRVSCGV | NA | Prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1722 | NA | NA | CASLSCR | NA | Prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1723 | NA | NA | CSGGKVLDC | NA | Prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1724 | NA | NA | CASLSCR | NA | Premalignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1725 | NA | NA | CSGGKVLDC | NA | Premalignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1726 | NA | NA | CSMSAKKKC | NA | Malignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1727 | NA | NA | CKTRVSCGV | NA | Malignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |
| 1728 | NA | NA | CASLSCR | NA | Malignant prostate cancer | NA | NA | NA | NA | TRAMP mice bearing PPC1, M12, DU145 and LNCaP human prostate cancer xenograft tumors | Homing | NA | US 2007/0219134 A1 |