The prediction of DNA interacting residues (DIRs) from protein sequences is important for the functional annotation of proteins. DNAint is a user-friendly tool for the sequence-based prediction of DIRs and this is freely available for the acadamic use.

Example - I-PPOL HOMING ENDONUCLEASE/DNA COMPLEX (PDB ID - 1A74)
---| Magenta - DNA | Blue - Protein | Green - Interacting residues |---

The standalone version (Windows OS based) of DNAint is available from HERE