Principal Scientist:

 
Dr. Vinod Chaudhari

Phone:

 
6665153

Contact Address

 

Medicinal Chemistry Lab,
3rd Floor, Main Building
vinod.jpg

Expertise:

Medicinal Chemistry, Drug discovery, Synthetic Organic Chemistry, Carbohydrate Chemistry.

Profile:

Dr. Vinod Chaudhari is a Medicinal Chemist, received his PhD in Synthetic Organic/Carbohydrate Chemistry from University of Pune, Pune and subsequently moved to University Joseph Furrier (CNRS), Grenoble, France for a Post-Doctoral training on Synthetic Organic Chemistry. He has over 12 years of Synthetic and Medicinal Chemistry research experience in Indian Industries. He has worked at Lupin Research Park Pune, Aurigene Discovery Technology Ltdand Zydus Research Centre, prior to joining CSIR-IMTECH Jan 2019. Vinod has experience in leading drug discovery teams that successfully delivered several preclinical/clinical development candidates. He has experience in working with various target classes including GPCRs, Ion channels and Kinases, across different therapeutic areas like Metabolic disorders, Oncology, Respiratorydiseases, Inflammation, and Neurosciences.

At CSIR-IMTECH his research group focus will be on new drug discovery in the different therapeutic areas like of Antimicrobial resistance, Infectious and Neglected diseases. Currently working on design and synthesis of novel small molecules targeting different targets for the therapeutic area of Respiratory infectious diseases particularly tuberculosis (TB) andAntimicrobial resistance (AMR).His research focus will be also on total synthesis of biologically active natural/unnatural products using chiral template derived from carbohydrate. .

Major Publications

  • Discovery of 1H-pyrazolo[3,4-b]pyridines as potent dual orexin receptor antagonists (DORAs)Dirk Behnke, Cotesta Simona, Samuel Hintermann, Markus Fendt, Christine E. Gee, Laura H. Jacobson, Grit Laue, Meyer Arndt, Trixie Wagner, Sangamesh Badiger, Vinod Chaudhari, Murali Chebrolu, Chetan Pandit, Daniel Hoyer and Claudia Betschart. Bioorganic & Medicinal Chemistry Letters, 2015, 25 (23), 5555–5560.
  • Identification of a Novel Series of Orexin Receptor Antagonists with a Distinct Effect on Sleep Architecture for the Treatment of Insomnia Claudia Betschart, Samuel Hintermann, Dirk Behnke, Cotesta Simona, Markus Fendt, Christine E. Gee, Laura H. Jacobson, Grit Laue, Silvio Ofner, Sangamesh Badiger, Vinod Chaudhari, Chetan Pandit, Juergen Wagner and Daniel Hoyer; J. Med. Chem.,2013, 56 (19), 7590–7607.
  • An Efficient Synthesis of D-erythro- and D-threo-Sphingosine from D-Glucose: Olefin Cross-Metathesis Approach. Vinod D. Chaudhari, K. S. Ajish Kumar, and Dilip D. Dhavale. Organic Letters2005, 7, 5805-5807.

For Complete Profile: Click Here